whole genome, one cell at a time
Explore Our Research
WHAT WE ASK
Embryos start out life as a single cell but quickly diversify into the bones, muscles, neurons, and skin that make up a plant or animal. How do these diverse cell types arise? Our lab is interested in how cohorts of genes orchestrate these developmental processes. In the process, we discover novel modes of genetic regulatory control.
HOW WE ASK IT
We address biological questions using cutting-edge technologies like single-cell-resolution genomics and single-molecule imaging. Our research combines hypothesis-driven molecular experimentation and computational analysis. Researchers in our group are trained in genetics, molecular biology, and computational biology.
MEET THE WORMS
We use the microscopic nematode worm, Caenorhabditis elegans, as a genetic model. C. elegans are popular among researchers for their rapid and invariant embryonic development that can be viewed under the microscope over the course of a day. C. elegans were the first animal species to have their genome fully sequenced and are excellent for use in genome-wide studies. Furthermore, a large community of C. elegans researchers has worked together to develop resources that allow for precise genetic manipulation and experimentation. Because the characteristics and machinery of gene regulatory control are shared across animals, the things we learn in this worm model are relevant to human health.
Detailed Research Projects
Meet The Scientists
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Located at Colorado State University
in beautiful Colorado!